The error may look like…
HTTP Error 404.3 - Not Found The page you are requesting cannot be served because of the extension configuration. If the page is a script, add a handler. If the file should be downloaded, add a MIME map.
This is because PHP has not been enabled for your site and IIS does not know how to process .php files. You may enable PHP in the control panel in the “Handler Mappings” tab for your website. Once PHP is enabled, the error will go away and your website will load properly.